My case is paraparesis For Original details of case click below link https://srianugna.blogspot.com/2020/05/hello-everyone.html Cheif complaints  Bilateral lower limb weakness since 20 days  Started proximal later progressed to bilateral distal region Bilateral edema which is non pitting  Difficulty in squatting and getting up Difficulty in wearing chepals NO H/O DIFFICULTY IN COMBING HAIR , BUTTONING AND UNBUTTONING SHIRT NO H/O CRANIAL NERVE INVOLVEMENT According to me Neurological weakness due to 1. Upper motor neuron 2. Basal ganglia and cerebellum 3. Lower motor neurons  Other causes of weakness might be  Systemic  Drug induced Vitamin deficiency  Autoimmune diseases Thyroid condition We will rule out one by one so that we can come to conclude diagnosis Upper motor neuron lesions means any lesion from cerebral cortex to  Spinal cord Symptoms of upper motor lesion are Hypertonia Hyperreflexia Exaggerated deep tendon reflexes Babinski sign positive No Loss of power In our patient no

I've been given this case to solve in an attempt to understand the topic of "patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and treatment. Original findings of the case link below: https://classworkdecjan.blogspot.com/2019/05/42-f-with-severe-regular-edema-with_17.html?m=1 Main complaints: 1.Swelling 2.Increased pain tolerance 3.Sleep deprivation 4.Decreased frequency of urination Complaints in detail history: 1.SWELLING:  Onset: present since one year age Mostly confined to face and abdomen Aggrevating factors: Exercise, smoking, some foods like favabeans and on taking drugs like anti malarials, sulfa drugs Relived by Cimetidine She had history of dark urine    Differential diagnosis could be Angioedema  Congenital heart disease Renal failure  G6PD deficiency   On history she had dark urine whick is suggestive of UTI or G6PD deficiency And swelling on anti malarials